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dc.creatorCelaya, Liliana Soledad
dc.creatorViturro, Carmen Ines
dc.creatorSilva, Luis R.
dc.date.accessioned2023-08-22T23:06:55Z
dc.date.available2023-08-22T23:06:55Z
dc.date.issued2019-06-25
dc.identifier.citationCelaya, L.S., Viturro, C. I. y Silva, L. R. (2019). Acantholippia salsoloides : phytochemical composition and biological potential of a thujonic population. Natural Product Communications. Estados Unidos : Sage Publications, 14 (6), pp. 1-7.es_AR
dc.identifier.issn1555-9475
dc.identifier.other12380
dc.identifier.otherCCPI-CNyE-A-089
dc.identifier.urihttps://hdl.handle.net/20.500.12219/4967
dc.descriptionFil: Celaya, Liliana Soledad. Universidad Nacional de Jujuy. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina.es_AR
dc.descriptionFil: Celaya, Liliana Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina.
dc.descriptionFil: Celaya, Liliana Soledad. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Departamento de Ingeniería Química ; Argentina.
dc.descriptionFil: Celaya, Liliana Soledad. Universidade do Porto. Faculdade de Farmácia. Laboratório de Farmacognosia; Portugal.
dc.descriptionFil: Viturro, Carmen Ines. Universidad Nacional de Jujuy. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina.
dc.descriptionFil: Viturro, Carmen Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Interdisciplinario de Investigaciones en Tecnologías y Desarrollo Social para el Noa; Argentina.
dc.descriptionFil: Silva, Luis R. Universidade da Beira Interior. Centro de Investigação em Ciências da Saúde; Portugal.
dc.description.abstractAcantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine. A. salsoloides attributes its common name “rica-rica” to the fresh and sweet fragrance of the plant. In this work, 2 different polar extracts and the essential oil of a selected rica-rica population were studied. The phenolic composition was analyzed by high-performance liquid chromatography diode array detector; the essential oil profile was determined by gas-chromatography ion-trap mass spectrometry/flame ionization detection. For all extracts, the antibacterial potential was performed by in vitro assays; the antioxidant and α-glucosidase inhibition were determined in decoction and hydroethanolic extracts. The volatile profile allowed the identification of 26 volatile compounds, β-thujone (84%) being the major one in this rica-rica population. Eighteen phenolic compounds were identified; isoferulic acid (16%-18%) and cynaroside (45%-47%) were the larger ones. In a general way, the hydroethanolic extract was more active against Staphylococcus aureus and Micrococcus luteus (minimum inhibitory concentrations= 0.3- 1.3 mg/mL). Both polar extracts have strong antiradical activities although decoction extract proved to be more active against DPPH• (half-maximal inhibitory concentration [IC50] =36 μg/mL) and O2 ●−(IC50 =28 μg/mL) while hydroethanolic extract shows higher action over α-glucosidase (IC50 =217 μg/mL). The results suggest that A. salsoloides leaves and flowers may be an interesting source of natural antioxidants, antidiabetics, or antimicrobials, and could be used in dietary supplements, medicinal products and pharmaceutical formulations.es_AR
dc.formatapplication/pdf
dc.format.extent360 KB
dc.language.isoenges_AR
dc.publisherSage Publicationses_AR
dc.relationinfo:eu-repo/semantics/altIdentifier/hdl/http://hdl.handle.net/11336/105425
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1177/1934578X19858542
dc.relationinfo:eu-repo/semantics/altIdentifier/urn/http://journals.sagepub.com/doi/10.1177/1934578X19858542
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAcantholippia salsoloideses_AR
dc.subjectβ-thujonees_AR
dc.subjectIsoferulic acides_AR
dc.subjectCynarosidees_AR
dc.subjectBiological actiones_AR
dc.titleAcantholippia salsoloides : phytochemical composition and biological potential of a thujonic populationes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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